PET/CT > Normal Activity > Thorax > Heart


Normal heart


With sufficient fasting (at least 6 hours) the myocardium theoretically shifts from glucose to fatty acid metabolism to fulfill its energy requirements and FDG myocardial activity should decrease to blood pool levels. However, in practice, variable and non-uniform myocardial activity is demonstrated even following an overnight fast. This is thought likely related to the non-uniform myocardial transition from glucose to fatty acid metabolism. This transition typically occurs last in the left ventricular base. Because of the wide variation in activity, detection of myocardial pathology with FDG on whole-body PET imaging is insensitive.

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