Wilson's disease

1. Pathogenesis:

• May cause enlarged liver without focal disease. Inflammation can progress to cirrhosis.
   
• Is a hereditary disease of copper metabolism. Copper deposits in the liver, the cornea, and the brain (especially the lenticular nucleus).

2. Radiographic findings:

• CT: liver is hyperdense. CT findings appear identical to those of hemochromatosis.
  
  
• MRI: an increase in signal on T1-weighted images with a decrease on T2-weighted images.