Radiobiology > Biologic Interactions > Translocations


Translocations

Reciprocal exchange of chromosomal fragments between two or more chromosomes. 

Symmetric translocation may be compatible with a normal phenotype, though likely to have reproductive failures.

Offspring may receive only one of the rearranged chromosomes – thus becoming genomically incomplete with regard to that chromosome.  The phenotypic manifestations of receiving such an imbalanced translocation include miscarriage or aberrant physical and/or mental development.



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