Porencephaly and encephalomalacia may appear similar to schizencephaly but are the result of parenchymal injury to previously developed structures. Before the end of the second trimester, glial scar formation does not occur and focal injury results in the development of a fluid filled space, porencephaly, that would not be lined by only gray matter. During the third trimester, parenchymal injury incites glial scar, encephalomalacia, which appears as high T2 signal in the region of injury.