Radiobiology > Biologic Interactions > Cell Death


Cell Death

Cell death is operationally defined as loss of function, such as reproductive capacity for stem cells or synthesis of some specific product (enzyme, hormone, et cetera). Apoptosis is the process of programmed cell death - biochemical pathways within a cell leading to its own organized dismantling.

When DNA is damaged and not successfully repaired, the cell may die � cell death may occur immediately (interphase death) or during its attempt to divide (mitotic or reproductive death) or after a few cell divisions (abortive colonies). 

Leukocytes are particularly susceptible to interphase death