GI Radiology > Spleen > Others > Splenomegaly

Splenomegaly

In the plain film above, the degree of splenomegaly is readily appreciable. The splenic shadow extends to the iliac crest, in comparison to normal physiologic spleen size which extends only to the costal margin. A comparison 3D reconstructed coronal image of the same patient demonstrates spleen size in comparison to the liver margin. Shown below are sequential axial CT images demonstrating the size of the spleen.

The differential diagnosis for an enlarged spleen includes: Gaucher's, Thalassemia, spherocytosis, right sided heart failure, cirrhosis with portal, hypertension, myeloproliferative disease, leukemia, lymphoma, hematochromatosis, infection.