A constitutional disorder of bone is a developmental abnormality of bone which results in diffuse bony abnormalities. Germane to the discussion of constitutional bony disorders, the following are addressed in this section:

• skeletal dysplasias (achondroplasia)
• mucopolysaccharidoses
• osteogenesis imperfecta
• osteopetrosis
• neurofibromatosis
• Blount disease