Benign
Inflammatory Strictures
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Inflammatory strictures are usually caused by
reflux and generally present as focal areas of narrowing, most
commonly in the distal one-third of the esophagus.
In relatively mild strictures, a single, large diameter
balloon can be used to dilate the stricture without resorting to a
sequence of progressively larger balloons.
The maximum diameter balloon we use for esophageal
strictures is usually 20 mm.
In patients with tight strictures, the procedure is
performed initially with smaller diameter balloons, followed by
larger caliber balloons. In
a significant number of patients, the length of the stricture can
extend over several centimeters.
For these strictures, we prefer to use a relatively long
balloon ( 8 cm), as it is more likely to remain in position during
the procedure and not slide away from the stricture.
The use of a long balloon is also useful in patients with a
hiatal hernia who have strictures of the gastroesophageal (GE)junction.
Because of the hiatal hernia, the position of the GE
junction may change when the balloon is introduced, being lower or
higher than expected. When
a long balloon is used, the chances are better that the balloon
will straddle the stricture.
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When
multiple inflammatory strictures are present, it may be difficult
to position the guide wire, and, on occasion, a steerable catheter
(Biliary Stone Removal, Medi-tech Inc., Watertown, MA) may have to
be used to guide the wire. The multiple strictures can be dilated
simultaneously when a relatively long balloon catheter is used.
Malignant Strictures
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The technique of balloon dilation in cases with
an esophageal stricture from carcinoma is similar to the basic
procedure described earlier.
Care must be taken in choosing a balloon of appropriate
size, as a balloon that is too large increases the risk of
perforation. Also,
the balloon must be inflated slowly with small increments in
pressure to diminish the risks of perforation.
In our experience, even the dilation of malignant
strictures can be safe if the procedure is carefully performed.
Anastomotic
Strictures
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The technique for balloon dilation of an
esophageal anastomotic stricture is similar to the basic technique
described earlier. In
these patients it is frequently difficult to pass a guide wire
across the strictured anastomosis because this type of stricture
is less tapered than a benign inflammatory stricture.
Frequently, the esophageal wall is deformed.
A quantity of heaped up mucosa may be. present as a result
of the surgery and may prevent smooth advance of the guide wire.
Also, the anastomosis may lie at an angle to the
longitudinal axis of the esophagus if an end-to-side anastomosis
was created. Therefore,
it may take considerable manipulation to negotiate the stricture
and pass the guide wire. On
occasion a steerable catheter may have to be used to position the
guide wire.
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In patients with anastomotic strictures, the
choice of balloon size is based on two factors: the diameter of
the anastomosis originally created at surgery (if known) and the
diameter of the normal lumen above and below the stricture, as
determined from a predilation barium examination.
In practice, however, a tight stricture may sometimes
prevent distention of the gut distal to the narrowing, and it may
not be possible to measure the cross-sectional diameter on the
barium study. We
usually base our choice of the maximum balloon diameter on our
projection of the desirable anastomotic diameter to be achieved.
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In
our experience, high inflation pressures of the balloon are
usually required to dilate anastomotic strictures, and the
strictures may sometimes be quite resistant to dilation.
This is because a significant amount of scar tissue
frequently forms around the stricture.
It is probably because of this scar tissue that the chances
of perforation are quite low, even when inflations are performed
at high pressures.
Webs
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Webs of the upper esophagus are uncommon lesions
that may be detected incidentally on esophagograms.
In some patients, symptoms such as dysphagia may occur and
treatment may be required. Historically,
symptomatic webs have been treated with bougienage during
esophagoscopy, but can also be successfully treated with
fluoroscopically guided balloon dilation.
In our experience, the procedure is very simple and can
usually be performed in 10 minutes.
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The procedure is best performed when the patient
is placed in a lateral position.
Dilation is usually done with a 20 mm diameter balloon.
To make the procedure as comfortable as possible for the
patient, the shortest balloon catheter possible (3 cm or less)
should be used; a longer balloon may press on the cricopharyngeus
muscle during inflation, increasing the patient's tendency to
swallow reflexively and displace the centered balloon.
After the balloon is positioned over the web, it is quickly
inflated to maximum pressure to dilate the stenosis.
Fluoroscopically, one frequently sees an abrupt
disappearance of the "waist" on the balloon, and the patient
may feel a snap when the web tears open.
In the majority of patients, only one dilation is necessary
to treat the web. A
postprocedure barium examination of the esophagus is performed by
injecting barium suspension through the partially withdrawn,
deflated balloon catheter; typically the esophagus shows no
residual abnormalities.
Anastomotic
Leaks
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Disruption of a surgical anastomosis is a common
complication of cervical esophagogastrostomy or esophagocolonic
interposition, occurring in 6-33% of cases.
The leak usually occurs within a few days to 2 weeks after
surgery and may persist for several weeks or months.
It has been reported that empirical bougienage of the
leaking cervical anastomosis often stops drainage from the
cervical fistula within a few days.
A reasonable explanation for the effectiveness of this
therapy is that there is a narrowing of the leaking anastomosis
that is relieved by the dilation.
The narrowing may be caused by spasm, edema, or
inflammation associated with the leak or may result from the
surgeon's failure to create a sufficiently large orifice. The narrowing obstructs the flow of secretions through the
esophagus and forces them into the fistula.
Healing of the fistula is delayed as long as the esophageal
stenosis persists. dilation increases the luminal diameter of the
anastomosis, thus improving esophageal emptying.
This in turn reduces intraluminal pressure and facilitates
healing of the disruption (Fig. 3).
Fig.
3.
Effect of dilation on leaking anastomosis.
(A)
When there is a leak of the anastomotic suture line,
esophageal secretions are forced to escape chiefly through the
leak (large arrow) because of the partial obstruction caused by
the narrowed anastomosis. The flow of secretions keeps the
disruption open.
(B)
dilation with the balloon increases the anastomotic
diameter.
(C)
After dilation, flow in the esophageal lumen is better
(large arrow), and secretions are no longer forced through the
fistula. This promotes more rapid healing.
(de Lange, Shaffer, & Holt, ref. 2.
Reproduced by permission.)
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Bougienage is done blindly and may further
disrupt the anastomosis. Complications
are less likely to occur when the dilation is preformed under
fluoroscopic control. We
now routinely perform a balloon dilation in patients with these
leaking anastomoses and, on the average, healing of the fistula
occurs within a few days after the procedure.
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Before the dilation procedure, the anastomotic
fistula is visualized with a contrast study.
Because many patients aspirate shortly after surgery as a
result of neuromuscular incoordination or edema surrounding the
surgical site, barium suspension is used as contrast medium
because it leads to fewer complications when aspirated and
provides better anatomic detail than a water soluble contrast.
The extravasated barium is not retained but rather escapes
through the cutaneous fistula or gradually drains back into the
lumen of the gut.
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Once the anastomotic leak is identified, the
patient is rotated into the position that permits optimal
fluoroscopic visualization. The
patient's throat is sprayed with a topical anesthetic, and
premedication with a systemic sedative may be required.
Patients usually do not experience significant pain because
the tissues of the anastomosis are denervated by the surgery and
are therefore less sensitive.
A systemic analgesic is not ordinarily required.
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The
balloon technique is similar to the general technique described
earlier.
The diameter of the balloon used for dilation should
correspond to the diameter of the anastomosis created at surgery,
which is 20 mm in most cases.
The balloon is positioned across the anastomosis with the
central portion of the balloon at the leak.
Upon inflation one can frequently identify the waist-like
contour at the middle of the balloon that corresponds to the
narrowed anastomosis.
In general, the narrowing can easily be stretched with
little pressure of the balloon.
The balloon is left maximally inflated for approximately 3
minutes, after which it is deflated for a minute.
We usually repeat the inflation 2-3 times during the same
session, and the whole procedure usually takes approximately 30
minutes.
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