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Quiz

1. True or False: Alzheimer's disease affects >65% of patients with known dementia.
True
 False

2. Choose from the following: The process responsible for Alzheimer's disease begins focally in the _______________.
parietal lobes
 occipital lobes
 fronto/temporal lobes

3. True or False: Imaging is typically used to rule in the diagnosis of Alzheimer's disease.

True
 False

4. Choose from the following: On coronal T1-weighted MRI, one might see which of the following structures atrophied in an Alzheimer's disease patient?
cerebral peduncles
 cerebellar vermis
 parahippocampal gyrus

5. Choose from the following: Which of the following structures will show metabolic sparing on FDG PET of an individual with Alzheimer's disease?
basal ganglia
 amygdala
 hippocampus

6. True or False: It is estimated that in the U.S. 1 in 100 persons over the age of 60 has Parkinson's disease.
True
 False

7. Choose from the following: In addition to the substantia nigra, what other structure listed among the following will show neuronal loss in Parkinson's disease?
red nucleus
 ventral tegmentum
 hypoglossal nucleus
 none of the above

8. True or False: On axial T2-weighted MRI, decreased width of the pars compacta may be evident in patients with Parkinson's disease.
True
 False

9. Choose from the following: On PET imaging using 6-fluorodopa in a patient with Parkinson's disease, decreased uptake is most evident in the __________.
cingulate gyrus
 habenula
 fornix
 putamen

10. True or False: FDG PET imaging in Parkinson's disease shows diffuse cortical hypometabolism most marked in the parietooccipital cortex.
True
 False

11. Choose from the following: Huntington's disease is a genetically linked disorder with autosomal ____________ inheritance and __________ penetrance.
recessive; complete
 dominant; incomplete
 recessive; incomplete
 dominant; complete

12. True or False: Huntington's disease is characterized by the selective degeneration of medium sized spiny neurons within the striatum.
True
 False

13. Choose from the following: On CT, Huntington's disease appears as _________________________________.
Decrease in the convexity of the caudate heads bilaterally.
 Decrease in the relative volume of the lateral ventricles.
 Both A and B.
 Neither A nor B.

14. Choose from the following: To a lesser extent, what additional structure may exhibit atrophy on imaging in Huntington's disease?
cingulate gyrus
 mammilary bodies
 putamen
 massa intermedia

15. True or False: FDG PET in Huntington's disease may only reveal hypermetabolism in the caudate nucleus.
True
 False

16. Choose from the following: Pick's disease is the ________ most common neurodegenerative cortical dementia.
second
 third
 fourth
 Pick's disease is not a common neurodegenerative cortical dementia.

17. True of False: Pick's disease is a tauopathy that only affects the frontal lobe.
True
 False

18. Choose from the following: On MRI in Pick's disease, one might observe which of the following?
widening of the Sylvian fissure
 atrophy of the inferior frontal and superior temporal lobes
 sulcal prominence
 enlargement of the frontal horns of the lateral ventricles
 all of the above

19. Choose from the following: SPECT imaging in the frontal variant of Pick's disease may reveal hypoperfusion defects in the ______________.
anterolateral temporal lobe
 ventromedial frontal region
 hippocampal formation
 none of the above

20. True of False: Individuals with a neurodegenerative disease will become more common throughout your future medical career.
True
 False

Your score is out of 20.

Answers